FRAX Equation:
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The FRAX® score is a computer-based algorithm that estimates the 10-year probability of a major osteoporotic fracture (hip, clinical spine, humerus, or wrist fracture) and the 10-year probability of hip fracture. It was developed by the World Health Organization Collaborating Centre for Metabolic Bone Diseases at the University of Sheffield.
The calculator uses the FRAX algorithm:
Where:
Details: The FRAX score helps clinicians identify patients at high risk of osteoporotic fractures who may benefit from treatment. It provides a more personalized assessment than BMD alone.
Tips: Enter all required information. BMD is optional but increases accuracy. The calculator is validated for ages 40-90. Results should be interpreted by a healthcare professional.
Q1: What is considered a high FRAX score?
A: Generally, ≥20% for major osteoporotic fracture or ≥3% for hip fracture indicates high risk, but thresholds vary by country and guidelines.
Q2: Can FRAX be used without BMD?
A: Yes, FRAX can be calculated with clinical risk factors alone, but inclusion of BMD increases accuracy.
Q3: How often should FRAX be recalculated?
A: Reassessment every 2-5 years is reasonable, or when significant changes occur in risk factors.
Q4: Does FRAX apply to all ethnic groups?
A: FRAX has country-specific models for many populations. Use the model most appropriate for your patient.
Q5: Can FRAX predict treatment response?
A: No, FRAX predicts baseline risk. Treatment decisions should consider both baseline risk and expected treatment benefit.