Nkf Gfr Calculator

NKF GFR Equation:

\[ GFR = CKD-EPI\ formula \]

Serum Creatinine (Scr):

mg/dL

Age:

years

Gender:

Race:

Estimated GFR:

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1. What is the NKF GFR Calculator?

The NKF (National Kidney Foundation) GFR Calculator estimates glomerular filtration rate (GFR) using the CKD-EPI equation from serum creatinine, age, sex, and race. It's the recommended method for assessing kidney function by the National Kidney Foundation.

2. How Does the Calculator Work?

The calculator uses the CKD-EPI equation:

\[ GFR = 141 \times \min(Scr/\kappa, 1)^\alpha \times \max(Scr/\kappa, 1)^{-1.209} \times 0.993^{age} \times (1.018 \text{ if female}) \times (1.159 \text{ if black}) \]

Where:

\( Scr \) — Serum creatinine (mg/dL)
\( \kappa \) — 0.7 (female) or 0.9 (male)
\( \alpha \) — -0.329 (female) or -0.411 (male)
\( age \) — Age in years
1.018 — Female multiplier
1.159 — Black race multiplier

Explanation: The equation provides a more accurate estimate of kidney function across the full range of GFR values compared to older equations.

3. Importance of GFR Calculation

Details: GFR is the best overall index of kidney function. Accurate GFR estimation is essential for detecting kidney disease, monitoring progression, and making treatment decisions.

4. Using the Calculator

Tips: For most accurate results, use a fasting morning blood sample for creatinine measurement. Enter values exactly as reported by your lab.

5. Frequently Asked Questions (FAQ)

Q1: Why does the NKF recommend this calculator?
A: The CKD-EPI equation used here is more accurate than older equations, especially for people with near-normal kidney function.

Q2: How often should GFR be checked?
A: Frequency depends on risk factors - annually for high-risk individuals, more often if kidney disease is present.

Q3: What affects creatinine levels besides kidney function?
A: Muscle mass, diet (meat consumption), medications, and hydration status can all influence creatinine levels.

Q4: Can this calculator be used for children?
A: No, this calculator is validated only for adults (age 18+). Pediatric GFR estimation requires different equations.

Q5: What's the difference between GFR and eGFR?
A: GFR is the actual measurement, while eGFR is an estimate calculated from equations like this one.