Conversion Formula:
From: | To: |
The mg/hr to mL/hr conversion calculates the volumetric infusion rate (mL/hr) needed to deliver a specific medication dose (mg/hr) based on the drug concentration in blood (mg/mL). This is essential for precise medication administration in clinical settings.
The calculator uses the following equation:
Where:
Explanation: The equation converts a mass-based infusion rate to a volume-based rate using the known concentration of the drug in the bloodstream.
Details: Precise conversion between mass-based and volume-based infusion rates is critical for patient safety, especially for medications with narrow therapeutic windows or potent effects.
Tips: Enter the desired medication infusion rate in mg/hr and the known blood concentration in mg/mL. Both values must be positive numbers.
Q1: Why is this conversion important?
A: It ensures accurate delivery of medications when infusion pumps are programmed in mL/hr but dosing guidelines specify mg/hr.
Q2: How do I determine blood concentration?
A: Blood concentration is typically determined through therapeutic drug monitoring or based on known pharmacokinetic parameters.
Q3: Can this be used for any medication?
A: This conversion applies to medications administered intravenously where the blood concentration is known or can be estimated.
Q4: What about protein binding?
A: This calculator uses total blood concentration. For highly protein-bound drugs, free concentration may be more relevant but requires additional information.
Q5: How often should blood concentration be measured?
A: Frequency depends on the drug's half-life, therapeutic window, and patient factors. Consult clinical guidelines for specific medications.