1. What is Protein to Creatinine Ratio?

The Protein to Creatinine Ratio (PCR) is a simple test that measures the amount of protein in the urine compared to the amount of creatinine. It's used to estimate proteinuria (excess protein in urine) and monitor kidney function.

2. How Does the Calculator Work?

The calculator uses the PCR formula:

Where:

• Urine Protein — Measured in mg/dL
• Urine Creatinine — Measured in mg/dL

Explanation: The ratio corrects for variations in urine concentration, providing a more reliable estimate of protein excretion than random urine protein measurements.

3. Importance of PCR Calculation

Details: PCR is important for detecting and monitoring kidney disease, as proteinuria is a key marker of kidney damage. It's more convenient than 24-hour urine collections.

4. Using the Calculator

Tips: Enter both urine protein and urine creatinine values in mg/dL. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal PCR value?
A: Normal PCR is typically less than 0.2 mg/mg. Values between 0.2-3.5 may indicate moderate proteinuria, while values above 3.5 suggest nephrotic-range proteinuria.

Q2: How does PCR compare to 24-hour urine protein?
A: PCR correlates well with 24-hour urine protein excretion. A PCR of 1 mg/mg roughly equals 1 gram of protein in a 24-hour urine collection.

Q3: When should PCR be measured?
A: First morning void is preferred, but random samples are acceptable. Avoid testing after vigorous exercise or during menstruation.

Q4: Are there limitations to PCR?
A: PCR may be less accurate in people with very high or low muscle mass, as creatinine excretion depends on muscle mass.

Q5: Should PCR be used for all patients?
A: While useful for screening, some patients may still require 24-hour urine collections for precise quantification in certain clinical situations.